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Training in Experimental
Therapeutics in Critical Illness
Critical Care Medicine National Research Service Award (NRSA)
Overview
This NLHLBI-funded postgraduate training program offers motivated physicians and scientists interested in an academic career in Critical Care Medicine or related fields an excellent opportunity to work in one of the oldest and best established academic critical care medicine training programs nationwide in the world. This training program is multi-disciplinary and accepts up to 4 trainees per year, over a period of up to 3 years. Trainees should have completed training in anesthesiology, emergency medicine, internal medicine, or surgery. Training for a period of 1-3 years is provided in research theory and practice in basic science research relevant to the pathophysiology or treatment of critical illness. The program runs in parallel with our clinical Critical Care Medicine training program in adult CCM. Fellows can share a common clinical first year that leads to certification eligibility in Critical Care Medicine. This program uniquely encompasses both clinical and laboratory exposure via federally funded research projects in the fields of Immunobiology, Cellular and Organ-system Cardiopulmonary Physiology, and Outcomes Research in Healthcare Management. Examples of ongoing research include: molecular mechanisms of enterocyte intestinal epithelial barrier dysfunction; endothelial-vascular muscle cell interactions; inflammatory cell-mediated vascular endothelial interactions; myocardial function during ischemia and ventricular pacing; cardiopulmonary interactions in shock states; and long-term outcome of ventilator-dependent patients from critical illness; and the use of novel resuscitation techniques to improve survival and organ function in critical illness. These research plans are based on broad questions on which precise, well-targeted individual research training efforts can be developed. Interdisciplinary approach to investigation is a unique feature of our critical care medicine training program. The faculty form a diverse and expert group of senior scientists, all of whom have strong track records as effective basic science investigators and educators with long-term extramural funding for their research.
Training
in Pediatric Neurointensive Care & Resuscitation Research
T-32
National Institute Child Health and Human Development (NICHD)
Overview
The research activities and interests of the
Department of Critical Care Medicine continue to expand and grow.
During the past six months funding has increased by 21% as the
research faculty continue to confirm and develop their specific
scientific agendas. Dr. Mitchell P. Fink, Professor and Chairman
of the Department, was awarded several new contracts by Industrial
sponsors to continue research and product development along related
lines of investigation, including development of a novel anti-oxidant
resuscitation fluid and mechanistic studies into epithelial dysfunction
in sepsis and inflammation.
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