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Project Title:
Myocardial Ischemia and Vasospasm in Aneurysmal Subarachnoid Hemorrhage(SAH).
Funding Agency:
National Institutes of Health
Total Project Period:
April 4, 2004 – March 31, 2005
Principal Investigator:
Dr. Michael Horowitz
Co-Investigator(s):
Dr. Marie Baldisseri
Project Summary:
This project will prospectively evaluate the incidence of myocardial ischemia and infarct in the subarachmoid hemorrhage (SAH) population and determine whether the presence of myocardial ischemia significantly increases the risk of symptomatic vasospasm, a major complication following SAH. The central hypothesis is that there is a catecholamine surge of norepinephrine and epinephrine immediately after SAH. This provides a common mechanism associated with both vasospasm of the cerebral and myocardial vessels that increases secondary cerebral and myocardial infarct.
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