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Project Title:
Divergent Pathways of Cell Death After Brain Injury
Funding Agency:
National Institutes of Health
Total Project Period:
Feb 01, 2003 - Jan 31, 2008
Principal Investigator:
Robert Clark, MD
Co-Investigator(s):
Patrick Kochanek; Jun Chen, C.Edward Dixon, Steven G. Graham, Donald W.
Marion, Hector R. Wong, Joseph A. Carcillo, Simon C. Watkins
Project Summary:
The major goals of this project are to identify divergent pathways of cell death in experimental in vitro models, in vivo models of traumatic brain injury in adult rats, and in humans after traumatic brain injury. Variations within these pathways in the response to pharmacological and molecular therapies targeting cell death will also be examined. This represents a competitive renewal application for 1R01 NS38620.
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