Mingchen Song , MD, Ph.D.
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Titles:
NIH Training Fellow, Department of Critical Care Medicine

Lab Affiliation:  Kellum
Start Date: 
November 11, 2000
Anticipated End Date of Research Activities at Pitt: 
Unknown

Contact:
Email: songm@ccm.upmc.edu

Degrees:

POST GRADUATE EDUCATION
INSTITUTION AND LOCATION
DEGREE YEAR FIELD
Shanxi Medical University, Shanxi, China MD 1986 Clinical Medicine
Shanxi Medical University, Shanxi, China M.S. 1991 Respiratory Medicine
Beijing Medical University, Beijing, China Ph.D. 1997 Respiratory Medicine

Major Honors/Awards:

  • 2002 NIH Training grant
  • 2001 Seed Awards from Department of Anesthesiology and Critical Care Medicine, University of Pittsburgh School of Medicine
  • 2000 Award in Advancement of Science and Technology of Beijing
  • 1999 Young Science and Technology Study Award of Shanxi Province

Research Grants:

Title Source of Support
Blood Purification in Experimental Sepsis RenalTech International

Current Research Interest:

  • Blood purification in experimental sepsis
  • Mechanism of ethyl pyruvate on inflammation
  • Acidosis in animal and cell culture models

Publications:

  • Venkataraman R, Kellum JA, Song M, Schmigel J, Fink MP. Resuscitation with Ringer’s Ethyl Pyruvate Solution Prolongs Survival and Modulates Plasma Cytokine and Nitrite/Nitrate Concentrations in a Rat Model of Lipopolysaccharide-Induced Shock. Shock 18 (6): 507-512, 2002
  • Song M, Phelps DS. Comparison of SP-A and LPS Effects on the THP-1 Monocytic Cell Line. Am J Physiol (Lung Cell Mol Physiol), 279: L110-L117, 2000.
  • Song M, Phelps DS. Interaction of SP-A with LPS and Regulation on Inflammatory Cytokines in THP-1 Cell Line. Infection and Immunity 68: 6611-6617, 2000.
  • Song M, Bing H, Zhongmin Q, et al. Expression of Surfactant Proteins A, B and C in Lungs of Rats with Bleomycin-Induced Lung Fibrosis. Chin J. Tuberc Respir Dis. 21: 420-422, 1998.
  • Song M, Bing H, Zhongmin Q, et al. Expression of TNF-a and PDGF in Type II Epithelial Cells of Rats with Bleomycin-Induced Lung Fibrosis. Chin J Tuberc. Respir Dis 21: 221-223, 1998

Presentations at Major Meetings:

  • Song M, Kellum JA. Effect of Lactic Acid on LPS-Mediated Production of Inflammatory Cytokines and Nitric Oxide in RAW 264.7 Macrophages. Critical Care Medicine 30 (12-Suppl), Abstract #267, pg A54, December, 2002.
  • Song M, Kellum JA, Venkataraman R, Roberts G, Schmigel J, Zou Y, Kaldas H. Cytosorb Removes Inflammatory Medidators But Not Endotoxin in Vitro. Critical Care Medicine 30 (12-Suppl), Abstract #249, pg A48, December, 2002.
  • Song M, Kellum JA, Fink MP. Effect of Ethyl Pyruvate on Release of Inflammatory Cytokines and Nitric Oxide by LPS-stimulated Raw 264.7 Macrophages. Am J Respir Crit Care Med 165: A546, 2002.
  • Kellum JA, Song M. Effect of Acidosis on LPS-Mediated Production of Inflammatory Cytokines and Nitric Oxide in Raw Macrophages. Am J Respir Crit Care Med 165: A545, 2002.
  • Kellum JA, Song M, Venkataraman R. Improved Survival With Hemoadsorption in Endotoxin-Induced Hock in Rats. Am. J Respir Crit Care Med 165: A176, 2002.