The February 2009 issue of Critical Care Medicine has a fascinating article by Drs. Hülya Bayır, David Adelson, Stephen Wisniewski et al. from the Safar Center for Resuscitation Research (SCRR), the Children's Hospital of Pittsburgh, the Center for Free Radical and Antioxidant Health together with investigators at other medical centers. They describe a translational study testing the hypothesis that hypothermia attenuates oxidative damage, assessed in CSF by markers of lipid peroxidation, protein oxidation and antioxidant status after severe traumatic brain injury in infants and children, the first study to assess the effects of hypothermia on oxidative stress after clinical TBI. An accompanying editorial commends Dr. Bayir and her associates for their work which is expected to fuel the interest in drugs that have potent antioxidative effects.
                                                                       
On February 11, 2009, Dr. Bayır also gave Critical Care Medicine Grand Rounds at Pitt on "Oxidative Lipidomics in Traumatic Brain Injury: An Analysis of Fat(al) Consequences." To a very attentive audience she masterly reviewed recent SCRR studies and other prominent investigations in this rapidly expanding field of signalling roles of lipids and oxidized lipids in neuronal death after brain trauma. Dr. Bayır is, indeed, securing a prominent place for herself among the world leaders of CNS researchers. We congratulate her on a most successful career.