The prestigious journal Science published the article called "The Big Chill" in the August 10, 2007 issue. This article refers to hypothermia research performed at SCRR since the late Dr. Safar's days. It begins by describing Dr. Samuel Tisherman's work on dogs in hemorrhagic shock resulting in cardiac arrest, treated with massive infusion of ice cold saline, cooling body temperature from 37 to below 10 degrees C to permit time for surgical repair of the bleeding followed by rewarming during cardiopulmonary bypass and finally return of spontaneous circulation with retained brain function. Dr. Tisherman is currently working on funding and approval for use of this technique in human trauma victims who otherwise would die. The article next describes Dr. Patrick Kochanek's experimental work on use of hypothermia in traumatic brain injury. It also refers to Dr. Fritz Sterz' clinical study in Vienna that uses mild hypothermia in cardiac arrest patients to improve outcome. Dr. Sterz performed laboratory research on hypothermia at SCRR for three years before returning to his native Austria in the 1990s. Another Pitt faculty member mentioned in Science is Dr. David Adelson, neurosurgeon at UPMC Children's Hospital, who uses hypothermia for treatment of pediatric brain injury patients. While clinical researchers at other medical centers are also referred to in this three-page article, no other medical center received as much attention as the University of Pittsburgh and its prominent leaders in the field of hypothermia.