| Titles:
Adjunct Assistant Professor, CCM
Contact:
Email: rosenbloomaj@ccm.upmc.edu
Degrees:
POST GRADUATE EDUCATION
INSTITUTION AND LOCATION |
DEGREE |
YEAR |
FIELD |
| University of Maryland at Baltimore (UMAB) |
MD |
1980 |
Medicine |
| Residency: |
|
| Kaiser Foundation Hospital |
Resident |
1980-1983 |
Internal Medicine |
Fellowship:
|
|
| Stanford University |
Fellow |
1985-1986 |
Postdoctoral Fellow |
| University of Pittsburgh |
Fellow |
1987-1989 |
Critical Care Medicine |
| Board Certifications: |
Year |
American Board of Internal Medicine
|
1983 |
| Critical Care Medicine Subspecialty |
1989 |
Critical Care Medicine Subspecialty (10yr recertification)
|
1989 |
Positions:
1989-present, University of Pittsburgh Assistant Professor of CCM
2000-present, Carnegie Mellon University Laboratory Research Biologist,
Sensor & Technologies Center Affiliated Scientist, Microelectromechanical
System (MEMS)
Research Support:
- Optical probe systems for functional analysis
of cells in living tissues. 2001-2003, Keck Foundation
GOAL: Develop new fluorescent technology and microdialysis-based
microchip-compatible sensor systems for protein detection
- Nanoporous templates for large defect reduction
in SiC and GaN, nanocatalysis, magnetic clusters, and biotechnology.
2001-2004, Dept of Defense, Office of Naval Research
GOAL: Develop nanoporous Silicon Carbide for microchip compatible
semipermeable membrane for use in tissue or blood microdialysis
- Electronic Labels (Charge tags) for DNA STR
analysis 2001-2002, National Institutes of Justice (NIJ)
GOAL: Develop all-electronic DNA Sensing
- Mucosal Immunity in
HIV + individuals, 2003 – 2005, National Institutes of Health
GOAL: Define the role of immune cell populations, multiple cytokines
and chemokines in mucosal immunity and the effect of HIV infection
and treatment
Current Research Interest:
- Microchip-based sensor systems for the simultaneous
measurement of multiple biomolecules in vivo
- Detection of PNA-DNA binding by Dielectric
Resonance Spectroscopy
- Microdialysis of proteins: studies of recovery
efficiency and applications to human disease processes
- Nanoporous silicon carbide-a new material
for microdialysis and sensor membranes
- A bead-based immunoassay for anti-insulin antibodies
and applications to diabetes
- A passive fraction collector
for microdialysis
Publications:
- Rosenbloom AJ: Optimizing the drug treatment
of alcohol withdrawal. Amer J of Med 81:901-904; 1986.
- Rosenbloom AJ: Massive ST-segment elevation
without myocardial injury in a patient with fulminant hepatic
failure and cerebral edema. Chest 100:870; 1991.
- Rosenbloom AJ, Pinsky MR, Bryant JL, Shin A,
Tran T, Whiteside T: Leukocyte activation in the peripheral blood
of patients with cirrhosis of the liver and SIRS. Correlation
with serum interleukin-6 levels and organ dysfunction. JAMA 274:58-65,
1995.
- Rosenbloom AJ, Pinsky MR, Napolitano C, Nguyen
TS, Levann D, Ray B, Whiteside TL. Suppression of cytokine mediated
2-integrin activation on circulating neutrophils in critically
ill patients. J of Leukocyte Biology. 66:83-89, 1999.
- Mazariegos GV, Kramer
DJ, Lopez RC, Shakil AO, Rosenbloom AJ, Devera M, Giraldo M, Grogan
TA, Zhu Y, Fulmer ML, Amiot BP, Patzer JF: Safety observations
in phase I clinical evaluation of the excorp medical bioartifical
liver support system after the first four patients. ASAIO Journal
47:471-475, 2001.
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