| Titles:
Professor, Department of Critical Care Medicine
Associate Professor, Department of Medicine
Contact:
Email: lindenpk@ccm.upmc.edu
Degrees:
POST GRADUATE EDUCATION
INSTITUTION AND LOCATION |
DEGREE |
YEAR |
FIELD |
| Medical School: Boston Univ, Boston, MA |
DMD |
1975-1979 |
Dentistry |
| Hahnemann Medical College |
MD |
1982-1984 |
Medicine |
| Residency: |
|
St. Elizabeth Hospital, Boston, MA
|
Resident
|
7/80-6/82
|
Anesthesiology |
| George Washington Univ Med Center, Washington, |
Intern |
7/84-6/85 |
Internal Medicine |
| DCGeorge Washington Univ Med Center, Washington, DC |
Resident |
7/85-6/87 |
Internal Medicine |
Fellowship:
|
|
| George Washington Univ Med Center, Washington, DC |
Fellow |
7/87-6/88
|
Infectious Diseases
|
| Univ Health Center of Pittsburgh, Pittsburgh, PA |
Fellow |
7/88-6/89 |
Critical Care Medicine |
| Univ Health Center of Pittsburgh, Pittsburgh, PA |
Fellow |
7/89-6/90 |
Infectious Diseases |
| Board Certifications: |
|
ABIM
|
1987
|
Internal Medicine
|
| ABIM – Infectious Diseases |
1990 |
Infectious Diseases |
| ABIM – CCM |
1991 |
Critical Care Medicine |
Administrative Title
Critical Care Medicine Director, Liver Transplant ICU Service
Major Honors/Awards:
Nomination for Outstanding Faculty Critical Care Medicine
1997
President's Citation Award for Contributions to SCCM 1998
Clinical Trials Scholar Award 1999
Strathmore's Who's Who 2000
Research Grants:
| Title |
Source of Support |
| 2000 Randomized study of linezolid vs. vancomycin for bacteremia
due to Staphylococcus aureus. |
Pharmacia Upjohn |
| 2000 Multicenter open-label non-comparative study to assess
safety and efficacy of cidecin (daptomycin) in the treatment
of subjects with infections due to gram-positive bacteria that
are resistant to vancomycin, or who are otherwise refractory
to , or contraindicated for currently available therapy |
Cubist Pharmaceuticals |
| 2000 A multicenter, open-label randomized study to compare
the safety and efficacy of iv cidecin (daptomycin) with that
of vancomycin in the treatment of bacteremic infinfections due
to gram-positive bacteria |
Eli Lilly Pharmaceuticals |
| 2000 Prospective-randomized multicenter trial of pulmonary
artery catheter vs. central venous catheter for management of
respiratory distress syndrome and acute lung injury and prospective
randomized fluid-liberal vs. fluid conservative management of
acute lung injury and acute respiratory distress syndrome. PI:
Peter Linden, MD; Co-PI: Michael Donahoe, MD, Mitchell Fink,
MD Contract #N01-HR-16152 Project Period: 10/31/00-10/30/03
|
National Heart Lung and Blood Institute RFP No.
NHLBI-HR-01-01 ARDSNET |
| Phase II double-blind, randomized, placebo-controlled clinical
study of NOX-100 for the treatment of distributive shock due
to sepsis. |
Medinox, Inc |
| A randomized, double-blind, double-dummy Phase III comparative
study of Cidecin (daptomycin) and Zyvox (Linezolid) in the treatment
of hospitalized adults with suspected vancomycin-resistant enterococcal
infections. |
Cubist Pharmaceuticals |
| Phase 2 Evaluation of the Vitagen® Extracoporeal Liver
Assist Device (ELAD) in the Management of Patients with Fulminant
Hepatic Failure. Vitagen, Inc. |
Vitagen, Inc. |
Current Research Interest:
Nosocomial Infection
Sepsis
Artificial Liver Support
Publications:
- Linden P, Pasculle AW, Kramer DJ, Silverman
A, Kusne S, Dean J, Bompart F. Treatment of serious infection
due to vancomycin-resistant Enterococcus faecium with quinupristin/dalfopristin.
J Antimicrob Chemother 39(suppl A):1-7, 1997
- Linden P, Pasculle AW, Manez R, Kramer DJ,
Fung JJ, Pinna AD, Kusne S. Differences in outcome in patients
with bacteremia due to vancomycin-resistant Enterococcus faecium
and vancomycin susceptible Enterococcus faecium. Clin Inf Dis
22:663-70, 1996.
- Linden P, Williams P, Chan KM. Efficacy and
safety of amphotericin B lipid complex in solid-organ transplant
recipients with invasive fungal infection. Clin Transplantation
14:329-339, 2000.
- Linden PK, Moellering RC, Wood CA, Rehm SJ,
Flaherty J, Bompart F, Talbot GH. Treatment of vancomycin-resistant
Enterococcus faecium infections with quinupristin/dalfopristin.
Clin Infect Dis 33: 1816-1823, 2001.
Presentations at major meetings (past
calendar year)
- Vancomycin-resistant enterococcal infection
following liver transplantation. September 16, 2002 Strong Memorial
Hospital , University of Rochester, Visiting Professor, Rochester,
NY
- Current management of gram-positive infection
in the transplant recipient. October 21, 2002. Hokkaida University
Medical Center, Visiting Professor, Sapporo, Japan.
- Current management of gram-positive infection
in the transplant recipient. October 22, 2002. Kyoto University
Medical Center, Kyoto, Japan.
|
|
