Titles:
Medical Director, Division of Trauma Surgery UPMC - Presbyterian
Assistant Professor of Critical Care Medicine and Surgery University of Pittsburgh School of Medicine

Degrees:

POST GRADUATE EDUCATION INSTITUTION AND LOCATION	DEGREE	YEAR	FIELD
University of Pittsburgh, Pittsburgh, PA	MD	1988-1992	Medicine
Residency:
University of Pittsburgh, Pittsburgh, PA	Resident	1992-2001	Surgery
Fellowship:
University of Pittsburgh, Pittsburgh, PA	Fellow	2001-2002	Surgical Critical Care
Board Certifications:			Year
General Surgery			2002
Surgical Critical Care			2003

Research Grants:

Current Research Interest:
Resuscitation endpoints in trauma
Selective management of solid organ injury
Surgical nutrition

Peer reviewed publications:

• Zamora R, Vodovotz Y, Alarcon L, Betten B, Loughran PA, Aulak KS, Stuehr DJ, Gibson KF, Billiar TR.  Nitric oxide from the inducible nitric oxide synthase (iNOS) increases the expression of cytochrome P450 2E1 in iNOS-null hepatocytes in the absence of inflammatory stimuli.  Archives of Biochemistry and Biophysics 390:287-294, 2001.
• Zamora R, Alarcon L, Vodovotz Y, Betten B, Kim P, Gibson K, Billiar TR.  Nitric oxide suppresses the expression of Bcl-2 binding protein BNIP3 in hepatocytes, Journal of Biological Chemistry 276:46887-46895, 2001.
• Zamora R, Vodovotz Y, Aulak K, Kim P, Kane J 3rd, Alarcon L, Stuehr D, Billiar T.  A DNA microarray study of nitric oxide-induced genes in mouse hepatocytes: implications for hepatic heme oxygenase-1 expression in ischemia/reperfusion. Nitric Oxide 7:165-186, 2002.
• Harbrecht BG, Zenati MS, Alarcon LH, Ochoa JB, Puyana JC, Schuchert VD, Peitzman AB. Is outcome after blunt splenic injury in adults better in high-volume trauma centers? American Surgeon 71(11):942-8; discussion 948-9, 2005.
• Harbrecht BG, Zenati MS, Ochoa JB, Puyana JC, Alarcon LH, Peitzman AB. Evaluation of a 15-year experience with splenic injuries in a state trauma system. Surgery 141(2):229-38, 2007.  
• Sperry JL, Ochoa JB, Gunn SR, Alarcon LH, Minei JP,  Cuschieri J, Rosengart MR, Maier RV, Billiar TR, Peitzman AB, Moore EE and The Inflammation the Host Response to Injury Investigators. A FFP:PRBC transfusion ratio ≥ 1:1.5 is associated with a lower risk of mortality following massive transfusion.  J Trauma 65 (5):986 –993, 2008.
• Polanco P, Leon S, Pineda J, Puyana JC, Ochoa JB, Alarcon L, Harbrecht BG, Geller D, Peitzman AB. Hepatic resection in the management of complex injury to the liver.  J Trauma 65(6): 1264-1270, 2008.

Book chapters and reviews:

• Alarcon LH, Billiar TR and Simmons RL:  Nitric oxide, sepsis and the heart, in Lewis and Shah (ed): Endothelial Modulation of Cardiac Function, pp 71-90.  Amsterdam, Harwood Academic Publishers, 1997.
• Alarcon LH, Taylor BS, Billiar RL:  The role of nitric oxide in liver pathophysiology.  Progress in Liver Diseases, Boyer and Okner (ed), vol 15: 85-108.  Philadelphia, W.B. Saunders Company, 1997.
• Taylor BS, Alarcon LH, Billiar TR.  Inducible nitric oxide synthase in the liver:  regulation and function.  Biochemistry (Moscow) 63:766-778, 1998            
• Alarcon LH, Boone DC, Peitzman AB: Peripheral vascular injuries, in Peitzman AB, Rhodes M, Schwab WC and Yealy DM (ed): The Trauma Manual pp 338-347.  Boston, Lippincott-Raven Publishers, 1998.
• Alarcon LH, Townsend RN: Peripheral vascular injuries, in Peitzman AB, Rhodes M, Schwab, Yealy DM, Fabian TC (ed): The Trauma Manual (2nd edition) pp 340-351.  Philadelphia, Lippincott Williams & Wilkins Publishers, 2002.
• Alarcon LH, Peitzman AB.  The management of blunt splenic trauma (Spanish).  Puesta al dia en Urgencias, Emergencias y Catastrophes 3:161-167, 2002.
• Harbrecht BG, Alarcon LH, Peitzman AB:  Management of shock, in Moore EE, Feliciano DV, Mattox KL (ed):  Trauma (5th edition), pp 201-226.  New York, McGraw-Hill, 2004.
• Sarani B, Alarcon LH. Journal club critique: Effect of reducing interns' work hours on sleep, attentional failures, and serious medical errors in intensive care units. Critical Care  9:E3, 2005.
• Alarcon LH: Paracentesis and diagnostic peritoneal lavage, in Fink MP, Abraham E, Vincent JL, Kochanek P (ed): Textbook of Critical Care (5th edition) pp 1841-1844.  Elsevier, Philadelphia 2005.
• Alarcon LH, Fink MP: Physiologic monitoring of the surgical patient, in Brunicardi FC, Andersen DK, Billiar TR, Dunn DL, Hunter JG, Pollock RE (ed): Schwartz’s Principles of Surgery (8th edition) pp. 361-378.  McGraw Hill, New York 2005.
• Alarcon LH, Fink MP: Physiologic monitoring of the surgical patient, in Brunicardi FC, Andersen DK, Billiar TR, Dunn DL, Hunter JG, Pollock RE (ed): Schwartz's Manual of Surgery (8th edition) pp. 275-292.  McGraw Hill, New York 2006.
• Neal M, Bansal V, Alarcon L, Russavage J.  A wrench in the OR aided our amputation.  Contemporary Surgery 63: 39-41, 2007.
• Alarcon LH, Peitzman AP: Initial assessment and early resuscitation, in Britt LD, Trunkey DD, Feliciano DV (ed): Acute Care Surgery: Principles and Practice (1st edition) pp 3-23. Springer, New York 2007.
• Bansal V, Alarcon L. The approach and resuscitation of the general surgery patient, in Peitzman AB, Rhodes M, Schwab, Yealy DM, Fabian TC (ed): The Trauma Manual: Trauma and Acute Care Surgery (3rd edition) pp 585-589.  Philadelphia, Lippincott Williams & Wilkins Publishers, 2007.
• Levy RM, Alarcon LH, Frykberg ER. Peripheral vascular injuries, in Peitzman AB, Rhodes M, Schwab, Yealy DM, Fabian TC (ed): The Trauma Manual: Trauma and Acute Care Surgery (3rd edition) pp 355-369.  Philadelphia, Lippincott Williams & Wilkins Publishers, 2007.
• Alarcon LH, Fink MP.  Mediators of the inflammatory response, in Townsend CM, Beauchamp RD, Evers BM, Mattox KL (ed): Sabiston textbook of surgery : the biological basis of modern surgical practice (18th edition) pp 44-68. Philadelphia, Saunders/Elsevier, 2008.
• Mohan D, Milbrandt EB, Alarcon LH. Journal club critique: Black Hawk Down: The evolution of resuscitation strategies in massive traumatic hemorrhage.  Critical Care 12:305, 2008.
• Alarcon LH. Physiologic monitoring of the surgical patient, in Brunicardi FC, Andersen DK, Billiar TR, Dunn DL, Hunter JG, Pollock RE (ed): Schwartz’s Principles of Surgery (9th edition) pp. 343-358.  McGraw Hill, New York 2009.

Presentations at meetings:

• Non-operative management of penetrating thoraco-abdominal trauma, Panamerican Trauma Society meeting, Lima, Peru, November 2003.
• Percutaneous tracheostomy.  ENT Grand Rounds, University of Pittsburgh School of Medicine, March  2005.
• Surgical infection prevention: effective prevention strategies, at the 2005 UPMC Quality symposium: the power of prevention.  November 2005.
• Prevention of Surgical Site Infections.  Armstrong County Memorial Hospital, Kittanning, Pennsylvania.  May 1, 2006.
• Enteral nutrition in trauma patients. Panamerican Trauma Society meeting, Cartagena, Colombia November 2006.
• Percutaneous tracheostomy.  Panamerican Trauma Society meeting, Cartagena, Colombia November 2006.
• The management of shock in trauma.  Emergency Medicine Grand Rounds, University of Pittsburgh School of Medicine, March 2007.
• When is the trauma patient sick? Management of the patient with polytrauma (6th international meeting), Pittsburgh, September 2007.
• Vascular injuries. Management of the patient with polytrauma (6th international meeting), Pittsburgh, September 2007.
• Invited discussant for paper presentation at the American Association for the Surgery of Trauma meeting, Las Vegas, September 2007..
• Emergency department thoracotomy.  Emergency Medicine Grand Rounds, University of Pittsburgh School of Medicine, February 2009.
• Coagulopathy of trauma: time is of the essence.  Wheeling Hospital Symposium: The Issue of Time.  Wheeling, WV, April 2009.
• Management of the open abdomen.  American Academy of Professional Coders National Meeting, Las Vegas, April 2009.
• Trauma: Life in the ER and beyond.  American Academy of Professional Coders National Meeting, Las Vegas, April 2009.